# PERSPECTIVE
Recognizing Historical Injustices in Medicine and the Journal: Explaining Health Inequities — The Enduring Legacy of Historical Biases
D.S. Jones, E. Hammonds, J.P. Gone, and D. Williams
# ORIGINAL ARTICLES
Live, Attenuated, Tetravalent Butantan–Dengue Vaccine in Children and Adults
E.G. Kallás and Others
Skin Antisepsis before Surgical Fixation of Extremity Fractures
The PREP-IT Investigators
Trial of N-Acetyl-l-Leucine in Niemann–Pick Disease Type C
T. Bremova-Ertl and Others
CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema
H.J. Longhurst and Others
# REVIEW ARTICLE
Cardiac Implantable Electronic Devices
S.M. Al-Khatib
# IMAGES IN CLINICAL MEDICINE
Incarcerated Obturator Hernia
W. Yang and L. Peng455
Myocardial Bridging
J.N. Hourmozdi and D. Schimmel
# CLINICAL PROBLEM-SOLVING
Flipping the Switch
M.K. Finta, G. Dhaliwal, O.R. Albin, K.R. Ghani, and N. Houchens
# EDITORIALS
Three Dengue Vaccines — What Now?
S.B. Halstead464-465
Lister Revisited — Skin Antisepsis before Fracture Fixation
S.O. Rogers, , and R.P. Wenzel466-467
Science behind the Study: N-Acetyl-l-Leucine and Neurodegenerative Disease
C.J. Tifft
# MEDICINE AND SOCIETY
Medical Training Today: On Calling — From Privileged Professionals to Cogs of Capitalism?
L. Rosenbaum